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How Adaptive Clinical Trial Management Platforms, Digital Patient Twins, and AI Agents can Rewrite Clinical Development
Clinical Trials

How Adaptive Clinical Trial Management Platforms, Digital Patient Twins, and AI Agents can Rewrite Clinical Development

The phase model is the bottleneck We’ve all heard this a lot by now. Bringing a new drug or biologic to patients takes about ten years, costs $1–2 billion, and fails mo…

Melissa Bime October 7, 2026 Read article
Picking Endpoints That Survive Reality
Clinical Trials

Picking Endpoints That Survive Reality

Endpoints are the key outcomes by which we judge a trial or product’s success are the compass guiding clinical development. An endpoint that “survives reality” is…

Melissa Bime January 9, 2026 Read article
Modeling the Human Body
Clinical Trials

Modeling the Human Body

Systems Biology – Integrating Organs and Networks The human body is not simply a collection of independent organs; it is a complex system of interconnected networks spanning…

Melissa Bime November 7, 2025 Read article
Validating Digital Patient Twins for Clinical Trial Decision Support
Clinical Trials

Validating Digital Patient Twins for Clinical Trial Decision Support

Patient twin models, also called digital patient twins, are changing how teams run clinical trial simulations. By mirroring real patient characteristics and outcomes, they help spo…

Melissa Bime November 5, 2025 Read article
Could this finally be the solution to archeiving diversity in clinical trials?
Clinical Trials

Could this finally be the solution to archeiving diversity in clinical trials?

Clinical trials have historically struggled to include participants who reflect the full spectrum of the patient population. When large swaths of people (whether defined by race, e…

Melissa Bime October 27, 2025 Read article
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